An accomplished engraver, Bartolozzi first trained in Florence. Bartolozzi was responsible for the popularising of the stipple process of color engraving which uses a 'dotted' technique thus eliminating the harsh contours of the line engraving. This method was particularly suited to the soft interpretationss of the Old Masters that were favored by the engravers of the 18th century.
Bartolozzi's most celebrated Old Master engravings are after Guercino (1591- 1666), whose drawings he engraved in 1772. Bartolozzi spent the second half of his life living and working in London, where he reproduced much of the work of his European contemporaries, Cipriani, Copley and Kaufmann.