Born in Fayette, Missouri, American Regionalist Roger Medearis studied with Thomas Hart Benton and John deMartelly at the Kansas City Art Institute during the 1930s and 1940s. Benton introduced Medearis to the American Artists Galleries, which sold his works while he was still a student.
After serving in World War II, Medearis exhibited in New York to favorable reviews. Eventually, he abandoned the art world to concentrate on a successful business career. In 1969 he retired from business and re-devoted himself to painting.