Born in Leeds, England, Ascher came to the US and studied at the New York School of Applied Design for Women, Hunter College, and the Art Students League.
A printmaker and painter, Ascher took part in many multicultural group exchange exhibitions such as with Japanese Women Artists in 1960, and Argentine Artists in 1963. In 1973 her 30 year retrospective was held in New York at the National Arts Club and her work was also exhibited at the Metropolitan Museum of Art in 1979.
Ascher was honored with the artists prize at the International Women's Year Awards in 1975; she is particularly remembered as the author of "Twelve Women of the New Testament and Early Church", produced with 25 portfolios. She served as the President of the American Society of Contemporary Artists from 1973 to 1975.